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Trypanosoma cruzi subverts the sphingomyelinase-mediated plasma membrane repair pathway for cell invasion
Upon host cell contact, the protozoan parasite Trypanosoma cruzi triggers cytosolic Ca(2+) transients that induce exocytosis of lysosomes, a process required for cell invasion. However, the exact mechanism by which lysosomal exocytosis mediates T. cruzi internalization remains unclear. We show that...
Autores principales: | Fernandes, Maria Cecilia, Cortez, Mauro, Flannery, Andrew R., Tam, Christina, Mortara, Renato A., Andrews, Norma W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092353/ https://www.ncbi.nlm.nih.gov/pubmed/21536739 http://dx.doi.org/10.1084/jem.20102518 |
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