Genetic Variance in Uncoupling Protein 2 in Relation to Obesity, Type 2 Diabetes, and Related Metabolic Traits: Focus on the Functional −866G>A Promoter Variant (rs659366)

Uncoupling proteins (UCPs) are mitochondrial proteins able to dissipate the proton gradient of the inner mitochondrial membrane when activated. This decreases ATP-generation through oxidation of fuels and may theoretically decrease energy expenditure leading to obesity. Evidence from Ucp((−/−)) mice...

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Detalles Bibliográficos
Autor principal: Dalgaard, Louise T.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092578/
https://www.ncbi.nlm.nih.gov/pubmed/21603268
http://dx.doi.org/10.1155/2011/340241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092578/
https://www.ncbi.nlm.nih.gov/pubmed/21603268
http://dx.doi.org/10.1155/2011/340241

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