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Urate Oxidase Purification by Salting-in Crystallization: Towards an Alternative to Chromatography

BACKGROUND: Rasburicase (Fasturtec® or Elitek®, Sanofi-Aventis), the recombinant form of urate oxidase from Aspergillus flavus, is a therapeutic enzyme used to prevent or decrease the high levels of uric acid in blood that can occur as a result of chemotherapy. It is produced by Sanofi-Aventis and c...

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Detalles Bibliográficos
Autores principales:	Giffard, Marion, Ferté, Natalie, Ragot, François, El Hajji, Mohamed, Castro, Bertrand, Bonneté, Françoise
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092763/ https://www.ncbi.nlm.nih.gov/pubmed/21589929 http://dx.doi.org/10.1371/journal.pone.0019013

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