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A Translational Regulator, PUM2, Promotes Both Protein Stability and Kinase Activity of Aurora-A

Aurora-A, a centrosomal serine-threonine kinase, orchestrates several key aspects of cell division. However, the regulatory pathways for the protein stability and kinase activity of Aurora-A are still not completely understood. In this study, PUM2, an RNA-binding protein, is identified as a novel su...

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Detalles Bibliográficos
Autores principales: Huang, Yei-Hsuan, Wu, Chun-Chi, Chou, Chen-Kung, Huang, Chi-Ying F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092770/
https://www.ncbi.nlm.nih.gov/pubmed/21589936
http://dx.doi.org/10.1371/journal.pone.0019718

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