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A Translational Regulator, PUM2, Promotes Both Protein Stability and Kinase Activity of Aurora-A
Aurora-A, a centrosomal serine-threonine kinase, orchestrates several key aspects of cell division. However, the regulatory pathways for the protein stability and kinase activity of Aurora-A are still not completely understood. In this study, PUM2, an RNA-binding protein, is identified as a novel su...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092770/ https://www.ncbi.nlm.nih.gov/pubmed/21589936 http://dx.doi.org/10.1371/journal.pone.0019718 |