Fine mapping the KLK3 locus on chromosome 19q13.33 associated with prostate cancer susceptibility and PSA levels

Measurements of serum prostate-specific antigen (PSA) protein levels form the basis for a widely used test to screen men for prostate cancer. Germline variants in the gene that encodes the PSA protein (KLK3) have been shown to be associated with both serum PSA levels and prostate cancer. Based on a...

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Detalles Bibliográficos
Autores principales: Parikh, Hemang, Wang, Zhaoming, Pettigrew, Kerry A., Jia, Jinping, Daugherty, Sarah, Yeager, Meredith, Jacobs, Kevin B., Hutchinson, Amy, Burdett, Laura, Cullen, Michael, Qi, Liqun, Boland, Joseph, Collins, Irene, Albert, Thomas J., Vatten, Lars J., Hveem, Kristian, Njølstad, Inger, Cancel-Tassin, Geraldine, Cussenot, Olivier, Valeri, Antoine, Virtamo, Jarmo, Thun, Michael J., Feigelson, Heather Spencer, Diver, W. Ryan, Chatterjee, Nilanjan, Thomas, Gilles, Albanes, Demetrius, Chanock, Stephen J., Hunter, David J., Hoover, Robert, Hayes, Richard B., Berndt, Sonja I., Sampson, Joshua, Amundadottir, Laufey
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092924/
https://www.ncbi.nlm.nih.gov/pubmed/21318478
http://dx.doi.org/10.1007/s00439-011-0953-5

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