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Advances in Glucocorticoid-Induced Osteoporosis
Glucocorticoid-induced osteoporosis (GIOP) is one of the most important side effects of glucocorticoid use, as it leads to an increased risk of fractures. Recently, many published studies have focused on the cellular and molecular mechanisms of bone metabolism, the pathophysiology of GIOP, and the i...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Current Science Inc.
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092927/ https://www.ncbi.nlm.nih.gov/pubmed/21365209 http://dx.doi.org/10.1007/s11926-011-0173-y |
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author | den Uyl, Debby Bultink, Irene E. M. Lems, Willem F. |
author_facet | den Uyl, Debby Bultink, Irene E. M. Lems, Willem F. |
author_sort | den Uyl, Debby |
collection | PubMed |
description | Glucocorticoid-induced osteoporosis (GIOP) is one of the most important side effects of glucocorticoid use, as it leads to an increased risk of fractures. Recently, many published studies have focused on the cellular and molecular mechanisms of bone metabolism, the pathophysiology of GIOP, and the intervention options to prevent GIOP. In this review, recent advances in GIOP are summarized, particularly recent progress in our understanding of the mechanisms of GIOP resulting in improved insight that might result in the development of new treatment options in the near future. |
format | Text |
id | pubmed-3092927 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Current Science Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-30929272011-06-07 Advances in Glucocorticoid-Induced Osteoporosis den Uyl, Debby Bultink, Irene E. M. Lems, Willem F. Curr Rheumatol Rep Article Glucocorticoid-induced osteoporosis (GIOP) is one of the most important side effects of glucocorticoid use, as it leads to an increased risk of fractures. Recently, many published studies have focused on the cellular and molecular mechanisms of bone metabolism, the pathophysiology of GIOP, and the intervention options to prevent GIOP. In this review, recent advances in GIOP are summarized, particularly recent progress in our understanding of the mechanisms of GIOP resulting in improved insight that might result in the development of new treatment options in the near future. Current Science Inc. 2011-03-02 2011 /pmc/articles/PMC3092927/ /pubmed/21365209 http://dx.doi.org/10.1007/s11926-011-0173-y Text en © The Author(s) 2011 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. |
spellingShingle | Article den Uyl, Debby Bultink, Irene E. M. Lems, Willem F. Advances in Glucocorticoid-Induced Osteoporosis |
title | Advances in Glucocorticoid-Induced Osteoporosis |
title_full | Advances in Glucocorticoid-Induced Osteoporosis |
title_fullStr | Advances in Glucocorticoid-Induced Osteoporosis |
title_full_unstemmed | Advances in Glucocorticoid-Induced Osteoporosis |
title_short | Advances in Glucocorticoid-Induced Osteoporosis |
title_sort | advances in glucocorticoid-induced osteoporosis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092927/ https://www.ncbi.nlm.nih.gov/pubmed/21365209 http://dx.doi.org/10.1007/s11926-011-0173-y |
work_keys_str_mv | AT denuyldebby advancesinglucocorticoidinducedosteoporosis AT bultinkireneem advancesinglucocorticoidinducedosteoporosis AT lemswillemf advancesinglucocorticoidinducedosteoporosis |