Polarographic determination of certain cephalosporins in pharmaceutical preparations

Polarographic methods have been developed for the determination of two cephalosporins namely cefotaxime (CTX) and ceftriaxone (CTR) in pharmaceutical formulations. Well defined peaks at potentials –1.432 V vs. SCE for CTX and –1.627 V vs. SCE for CTR were obtained in the presence of tungsten (VI). T...

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Detalles Bibliográficos
Autores principales: Guru Prasad, A.R., Rao, V.S.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093099/
https://www.ncbi.nlm.nih.gov/pubmed/21589769
Descripción
Sumario:Polarographic methods have been developed for the determination of two cephalosporins namely cefotaxime (CTX) and ceftriaxone (CTR) in pharmaceutical formulations. Well defined peaks at potentials –1.432 V vs. SCE for CTX and –1.627 V vs. SCE for CTR were obtained in the presence of tungsten (VI). The method has been successfully applied for the determination of above mentioned cephalosporins in commercial dosage forms. The salient features of this investigation are presented in this communication.

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