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Feather bedding and childhood asthma associated with house dust mite sensitisation: a randomised controlled trial

INTRODUCTION: Observational studies report inverse associations between the use of feather upper bedding (pillow and/or quilt) and asthma symptoms but there is no randomised controlled trial (RCT) evidence assessing the role of feather upper bedding as a secondary prevention measure. OBJECTIVE: To d...

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Autores principales: Glasgow, Nicholas J, Ponsonby, Anne-Louise, Kemp, Andrew, Tovey, Euan, van Asperen, Peter, McKay, Karen, Forbes, Samantha
Formato: Texto
Lenguaje:English
Publicado: BMJ Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093241/
https://www.ncbi.nlm.nih.gov/pubmed/21451166
http://dx.doi.org/10.1136/adc.2010.189696
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author Glasgow, Nicholas J
Ponsonby, Anne-Louise
Kemp, Andrew
Tovey, Euan
van Asperen, Peter
McKay, Karen
Forbes, Samantha
author_facet Glasgow, Nicholas J
Ponsonby, Anne-Louise
Kemp, Andrew
Tovey, Euan
van Asperen, Peter
McKay, Karen
Forbes, Samantha
author_sort Glasgow, Nicholas J
collection PubMed
description INTRODUCTION: Observational studies report inverse associations between the use of feather upper bedding (pillow and/or quilt) and asthma symptoms but there is no randomised controlled trial (RCT) evidence assessing the role of feather upper bedding as a secondary prevention measure. OBJECTIVE: To determine whether, among children not using feather upper bedding, a new feather pillow and feather quilt reduces asthma severity among house dust mite (HDM) sensitised children with asthma over a 1-year period compared with standard dust mite avoidance advice, and giving children a new mite-occlusive mattress cover. DESIGN: RCT. SETTING: The Calvary Hospital in the Australian Capital Territory and the Children's Hospital at Westmead, Sydney, New South Wales. PATIENTS: 197 children with HDM sensitisation and moderate to severe asthma. INTERVENTION: New upper bedding duck feather pillow and quilt and a mite-occlusive mattress cover (feather) versus standard care and a mite-occlusive mattress cover (standard). MAIN OUTCOME MEASURES: The proportion of children reporting four or more episodes of wheeze in the past year; an episode of speech-limiting wheeze; or one or more episodes of sleep disturbance caused by wheezing; and spirometry with challenge testing. Statistical analysis included multiple logistic and linear regression. RESULTS: No differences between groups were found for primary end points – frequent wheeze (OR 1.51, 95% CI 0.83 to 2.76, p=0.17), speech-limiting wheeze (OR 0.70, 95% CI 0.32 to 1.48, p=0.35), sleep disturbed because of wheezing (OR 1.17, 95% CI 0.64 to 2.13, p=0.61) or for any secondary end points. Secondary analyses indicated the intervention reduced the risk of sleep being disturbed because of wheezing and severe wheeze to a greater extent for children who slept supine. CONCLUSION: No differences in respiratory symptoms or lung function were observed 1 year after children with moderate–severe asthma and HDM sensitisation were given a mite-occlusive mattress cover and then received either feather upper bedding (pillow and quilt) or standard bedding care.
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spelling pubmed-30932412011-05-20 Feather bedding and childhood asthma associated with house dust mite sensitisation: a randomised controlled trial Glasgow, Nicholas J Ponsonby, Anne-Louise Kemp, Andrew Tovey, Euan van Asperen, Peter McKay, Karen Forbes, Samantha Arch Dis Child Original Articles INTRODUCTION: Observational studies report inverse associations between the use of feather upper bedding (pillow and/or quilt) and asthma symptoms but there is no randomised controlled trial (RCT) evidence assessing the role of feather upper bedding as a secondary prevention measure. OBJECTIVE: To determine whether, among children not using feather upper bedding, a new feather pillow and feather quilt reduces asthma severity among house dust mite (HDM) sensitised children with asthma over a 1-year period compared with standard dust mite avoidance advice, and giving children a new mite-occlusive mattress cover. DESIGN: RCT. SETTING: The Calvary Hospital in the Australian Capital Territory and the Children's Hospital at Westmead, Sydney, New South Wales. PATIENTS: 197 children with HDM sensitisation and moderate to severe asthma. INTERVENTION: New upper bedding duck feather pillow and quilt and a mite-occlusive mattress cover (feather) versus standard care and a mite-occlusive mattress cover (standard). MAIN OUTCOME MEASURES: The proportion of children reporting four or more episodes of wheeze in the past year; an episode of speech-limiting wheeze; or one or more episodes of sleep disturbance caused by wheezing; and spirometry with challenge testing. Statistical analysis included multiple logistic and linear regression. RESULTS: No differences between groups were found for primary end points – frequent wheeze (OR 1.51, 95% CI 0.83 to 2.76, p=0.17), speech-limiting wheeze (OR 0.70, 95% CI 0.32 to 1.48, p=0.35), sleep disturbed because of wheezing (OR 1.17, 95% CI 0.64 to 2.13, p=0.61) or for any secondary end points. Secondary analyses indicated the intervention reduced the risk of sleep being disturbed because of wheezing and severe wheeze to a greater extent for children who slept supine. CONCLUSION: No differences in respiratory symptoms or lung function were observed 1 year after children with moderate–severe asthma and HDM sensitisation were given a mite-occlusive mattress cover and then received either feather upper bedding (pillow and quilt) or standard bedding care. BMJ Group 2011-03-30 /pmc/articles/PMC3093241/ /pubmed/21451166 http://dx.doi.org/10.1136/adc.2010.189696 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license. See: http://creativecommons.org/licenses/by-nc/2.0/ and http://creativecommons.org/licenses/by-nc/2.0/legalcode.
spellingShingle Original Articles
Glasgow, Nicholas J
Ponsonby, Anne-Louise
Kemp, Andrew
Tovey, Euan
van Asperen, Peter
McKay, Karen
Forbes, Samantha
Feather bedding and childhood asthma associated with house dust mite sensitisation: a randomised controlled trial
title Feather bedding and childhood asthma associated with house dust mite sensitisation: a randomised controlled trial
title_full Feather bedding and childhood asthma associated with house dust mite sensitisation: a randomised controlled trial
title_fullStr Feather bedding and childhood asthma associated with house dust mite sensitisation: a randomised controlled trial
title_full_unstemmed Feather bedding and childhood asthma associated with house dust mite sensitisation: a randomised controlled trial
title_short Feather bedding and childhood asthma associated with house dust mite sensitisation: a randomised controlled trial
title_sort feather bedding and childhood asthma associated with house dust mite sensitisation: a randomised controlled trial
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093241/
https://www.ncbi.nlm.nih.gov/pubmed/21451166
http://dx.doi.org/10.1136/adc.2010.189696
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