Distinct and Shared Roles of β-Arrestin-1 and β-Arrestin-2 on the Regulation of C3a Receptor Signaling in Human Mast Cells

BACKGROUND: The complement component C3a induces degranulation in human mast cells via the activation of cell surface G protein coupled receptors (GPCR; C3aR). For most GPCRs, agonist-induced receptor phosphorylation leads to the recruitment of β-arrestin-1/β-arrestin-2; resulting in receptor desens...

Descripción completa

Detalles Bibliográficos
Autores principales: Vibhuti, Arpana, Gupta, Kshitij, Subramanian, Hariharan, Guo, Qiang, Ali, Hydar
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093384/
https://www.ncbi.nlm.nih.gov/pubmed/21589858
http://dx.doi.org/10.1371/journal.pone.0019585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093384/
https://www.ncbi.nlm.nih.gov/pubmed/21589858
http://dx.doi.org/10.1371/journal.pone.0019585

Ejemplares similares