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Distinct Roles of Bcl-2 and Bcl-Xl in the Apoptosis of Human Bone Marrow Mesenchymal Stem Cells during Differentiation
BACKGROUND: Adult mesenchymal stem cells (MSCs) can be maintained over extended periods of time before activation and differentiation. Little is known about the programs that sustain the survival of these cells. PRINCIPAL FINDINGS: Undifferentiated adult human MSCs (hMSCs) did not undergo apoptosis...
Autores principales: | Oliver, Lisa, Hue, Erika, Rossignol, Julien, Bougras, Gwenola, Hulin, Philippe, Naveilhan, Philippe, Heymann, Dominique, Lescaudron, Laurent, Vallette, François M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093403/ https://www.ncbi.nlm.nih.gov/pubmed/21589877 http://dx.doi.org/10.1371/journal.pone.0019820 |
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