A Motif Unique to the Human Dead-Box Protein DDX3 Is Important for Nucleic Acid Binding, ATP Hydrolysis, RNA/DNA Unwinding and HIV-1 Replication

DEAD-box proteins are enzymes endowed with nucleic acid-dependent ATPase, RNA translocase and unwinding activities. The human DEAD-box protein DDX3 has been shown to play important roles in tumor proliferation and viral infections. In particular, DDX3 has been identified as an essential cofactor for...

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Detalles Bibliográficos
Autores principales: Garbelli, Anna, Beermann, Sandra, Di Cicco, Giulia, Dietrich, Ursula, Maga, Giovanni
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093405/
https://www.ncbi.nlm.nih.gov/pubmed/21589879
http://dx.doi.org/10.1371/journal.pone.0019810

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