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T Cells from Programmed Death-1 Deficient Mice Respond Poorly to Mycobacterium tuberculosis Infection

BACKGROUND: Programmed Death-1 (PD-1; CD279) receptor molecule is widely believed to be a negative regulator predominantly expressed by exhausted/activated mouse T cells. Upon interaction with its ligands, PD-L1 and PD-L2, PD-1 inhibits activation of T cells and cytokine production, which has been d...

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Detalles Bibliográficos
Autores principales:	Tousif, Sultan, Singh, Yogesh, Prasad, Durbaka Vijaya Raghava, Sharma, Pawan, Kaer, Luc Van, Das, Gobardhan
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093409/ https://www.ncbi.nlm.nih.gov/pubmed/21589883 http://dx.doi.org/10.1371/journal.pone.0019864

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