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Selection and quantification of infection endpoints for trials of vaccines against intestinal helminths
Vaccines against human helminths are being developed but the choice of optimal parasitological endpoints and effect measures to assess their efficacy has received little attention. Assuming negative binomial distributions for the parasite counts, we rank the statistical power of three measures of ef...
Autores principales: | Alexander, Neal, Cundill, Bonnie, Sabatelli, Lorenzo, Bethony, Jeffrey M., Diemert, David, Hotez, Peter, Smith, Peter G., Rodrigues, Laura C., Brooker, Simon |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093614/ https://www.ncbi.nlm.nih.gov/pubmed/21435404 http://dx.doi.org/10.1016/j.vaccine.2011.03.026 |
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