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Genome-Wide Analysis of Self-Renewal in Drosophila Neural Stem Cells by Transgenic RNAi
The balance between stem cell self-renewal and differentiation is precisely controlled to ensure tissue homeostasis and prevent tumorigenesis. Here we use genome-wide transgenic RNAi to identify 620 genes potentially involved in controlling this balance in Drosophila neuroblasts. We quantify all phe...
Autores principales: | Neumüller, Ralph A., Richter, Constance, Fischer, Anja, Novatchkova, Maria, Neumüller, Klaus G., Knoblich, Juergen A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093620/ https://www.ncbi.nlm.nih.gov/pubmed/21549331 http://dx.doi.org/10.1016/j.stem.2011.02.022 |
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