Glucose-dependent insulinotropic peptide receptor overexpression in adrenocortical hyperplasia in MEN1 syndrome without loss of heterozygosity at the 11q13 locus

BACKGROUND: The molecular mechanisms involved in the genesis of the adrenocortical lesions seen in MEN1 syndrome (ACL-MEN1) remain poorly understood; loss of heterozygosity at 11q13 and somatic mutations of MEN1 are not usually found in these lesions. Thus, additional genes must be involved in MEN1...

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Detalles Bibliográficos
Autores principales: Costa, Marcia Helena Soares, Domenice, Sorahia, Toledo, Rodrigo Almeida, Lourenço, Delmar Muniz, Latronico, Ana Claudia, Pinto, Emilia Modolo, Toledo, Sergio Pereira Almeida, Mendonca, Berenice Bilharinho, Fragoso, Maria Candida Barisson Villares
Formato: Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2011
Materias:
Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093781/
https://www.ncbi.nlm.nih.gov/pubmed/21655742
http://dx.doi.org/10.1590/S1807-59322011000400002

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