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Synthetic conversion of a graded receptor signal into a tunable, reversible switch
The ability to engineer an all-or-none cellular response to a given signaling ligand is important in applications ranging from biosensing to tissue engineering. However, synthetic gene network ‘switches' have been limited in their applicability and tunability due to their reliance on specific c...
Autores principales: | Palani, Santhosh, Sarkar, Casim A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094063/ https://www.ncbi.nlm.nih.gov/pubmed/21451590 http://dx.doi.org/10.1038/msb.2011.13 |
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