Glucose metabolism determines resistance of cancer cells to bioenergetic crisis after cytochrome-c release

Many anticancer drugs activate caspases via the mitochondrial apoptosis pathway. Activation of this pathway triggers a concomitant bioenergetic crisis caused by the release of cytochrome-c (cyt-c). Cancer cells are able to evade these processes by altering metabolic and caspase activation pathways....

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Detalles Bibliográficos
Autores principales: Huber, Heinrich J, Dussmann, Heiko, Kilbride, Seán M, Rehm, Markus, Prehn, Jochen H M
Formato: Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094064/
https://www.ncbi.nlm.nih.gov/pubmed/21364572
http://dx.doi.org/10.1038/msb.2011.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094064/
https://www.ncbi.nlm.nih.gov/pubmed/21364572
http://dx.doi.org/10.1038/msb.2011.2

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