Gene therapy with tumor-specific promoter mediated suicide gene plus IL-12 gene enhanced tumor inhibition and prolonged host survival in a murine model of Lewis lung carcinoma

BACKGROUND: Gene therapy is a promising therapeutic approach for cancer. Targeted expression of desired therapeutic proteins within the tumor is the best approach to reduce toxicity and improve survival. This study is to establish a more effective and less toxic gene therapy of cancer. METHODS: Comb...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Yu, Hou, Jinxuan, Liu, Zhengchun, Yu, Haijun, Sun, Wenjie, Xiong, Jie, Liao, Zhengkai, Zhou, Fuxiang, Xie, Conghua, Zhou, Yunfeng
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094222/
https://www.ncbi.nlm.nih.gov/pubmed/21481255
http://dx.doi.org/10.1186/1479-5876-9-39

Ejemplares similares

Ejemplares similares