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Genome-wide screen for modifiers of Parkinson's disease genes in Drosophila
BACKGROUND: Mutations in parkin and PTEN-induced kinase 1 (Pink1) lead to autosomal recessive forms of Parkinson's disease (PD). parkin and Pink1 encode a ubiquitin-protein ligase and a mitochondrially localized serine/threonine kinase, respectively. Recent studies have implicated Parkin and Pi...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094290/ https://www.ncbi.nlm.nih.gov/pubmed/21504582 http://dx.doi.org/10.1186/1756-6606-4-17 |