High susceptibility of metastatic cells derived from human prostate and colon cancer cells to TRAIL and sensitization of TRAIL-insensitive primary cells to TRAIL by 4,5-dimethoxy-2-nitrobenzaldehyde

BACKGROUND: Tumor recurrence and metastasis develop as a result of tumors' acquisition of anti-apoptotic mechanisms and therefore, it is necessary to develop novel effective therapeutics against metastatic cancers. In this study, we showed the differential TRAIL responsiveness of human prostate...

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Detalles Bibliográficos
Autores principales: Kim, Hak-Bong, Kim, Mi-Ju, Kim, Dae-Young, Lee, Jae-Won, Bae, Jae-Ho, Kim, Dong-Wan, Kang, Chi-Dug, Kim, Sun-Hee
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094320/
https://www.ncbi.nlm.nih.gov/pubmed/21513580
http://dx.doi.org/10.1186/1476-4598-10-46

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