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Excessive Biologic Response to IFNβ Is Associated with Poor Treatment Response in Patients with Multiple Sclerosis

BACKGROUND: Interferon-beta (IFNβ) is used to inhibit disease activity in multiple sclerosis (MS), but its mechanisms of action are incompletely understood, individual treatment response varies, and biological markers predicting response to treatment have yet to be identified. METHODS: The relations...

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Detalles Bibliográficos
Autores principales: Rudick, Richard A., Rani, M. R. Sandhya, Xu, Yaomin, Lee, Jar-Chi, Na, Jie, Shrock, Jennifer, Josyula, Anupama, Fisher, Elizabeth, Ransohoff, Richard M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094352/
https://www.ncbi.nlm.nih.gov/pubmed/21602934
http://dx.doi.org/10.1371/journal.pone.0019262

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