Cargando…

Transcriptional Factor NF-κB as a Target for Therapy in Parkinson's Disease

Parkinson's disease (PD) is a neurodegenerative condition characterized by chronic inflammation. Nuclear factor κB (NF-κB) is a family of inducible transcription factors that are expressed in a wide variety of cells and tissues, including microglia, astrocytes, and neurons, and the classical NF...

Descripción completa

Detalles Bibliográficos
Autores principales:	Flood, Patrick M., Qian, Li, Peterson, Lynda J., Zhang, Feng, Shi, Jing-Shan, Gao, Hui-Ming, Hong, Jau-Shyong
Formato:	Texto
Lenguaje:	English
Publicado:	SAGE-Hindawi Access to Research 2011
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095232/ https://www.ncbi.nlm.nih.gov/pubmed/21603248 http://dx.doi.org/10.4061/2011/216298

Ejemplares similares

Oxidative Stress and Microglial Cells in Parkinson's Disease
por: Peterson, Lynda J., et al.
Publicado: (2012)

Parkinson's disease and exposure to infectious agents and pesticides and the occurrence of brain injuries: role of neuroinflammation.
por: Liu, Bin, et al.
Publicado: (2003)

Potential Benefits of Therapeutic Use of β2-Adrenergic Receptor Agonists in Neuroprotection and Parkinsonμs Disease
por: Peterson, Lynda, et al.
Publicado: (2014)

The Ubiquitination of NF-κB Subunits in the Control of Transcription
por: Collins, Patricia E., et al.
Publicado: (2016)

Transcriptional Control of Synaptic Plasticity by Transcription Factor NF-κB
por: Engelmann, Christian, et al.
Publicado: (2016)

Eugenol modulates the NOD1-NF-κB signaling pathway via targeting NF-κB protein in triple-negative breast cancer cells
por: Shi, Xiaoyu, et al.
Publicado: (2023)

Neuroinflammation and α-Synuclein Dysfunction Potentiate Each Other, Driving Chronic Progression of Neurodegeneration in a Mouse Model of Parkinson’s Disease
por: Gao, Hui-Ming, et al.
Publicado: (2011)

The regulation of sequence specific NF-κB DNA binding and transcription by IKKβ phosphorylation of NF-κB p50 at serine 80
por: Smith, Emma L, et al.
Publicado: (2019)

Regulation of the NF-κB-Mediated Transcription of Inflammatory Genes
por: Bhatt, Dev, et al.
Publicado: (2014)

The Transcription Factor NF-κB in Stem Cells and Development
por: Kaltschmidt, Christian, et al.
Publicado: (2021)

Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase
por: Qian, Li, et al.
Publicado: (2007)

Foxp3 Represses Retroviral Transcription by Targeting Both NF-κB and CREB Pathways
por: Grant, Christian, et al.
Publicado: (2006)

Triptolide Transcriptionally Represses HER2 in Ovarian Cancer Cells by Targeting NF-κB
por: Ou, Chien-Chih, et al.
Publicado: (2012)

UXT is a novel and essential cofactor in the NF-κB transcriptional enhanceosome
por: Sun, Shaogang, et al.
Publicado: (2007)

Extracellular ATP Activates Transcription Factor NF-κB through the P2Z Purinoreceptor by Selectively Targeting NF-κB p65 (RelA)
por: Ferrari, Davide, et al.
Publicado: (1997)

Late-onset Parkinsonism in NFκB/c-Rel-deficient mice
por: Baiguera, Cristina, et al.
Publicado: (2012)

Expression Analysis of NF-κB-Related lncRNAs in Parkinson’s Disease
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2021)

The Transcriptional Specificity of NF-κB Dimers Is Coded within the κB DNA Response Elements
por: Wang, Vivien Ya-Fan, et al.
Publicado: (2012)

NF-κB as potential target in the treatment of melanoma
por: Madonna, Gabriele, et al.
Publicado: (2012)

Targeting NF-κB Signaling for Multiple Myeloma
por: Wong, Ada Hang-Heng, et al.
Publicado: (2020)

Genomic locus proteomic screening identifies the NF-κB signaling pathway components NFκB1 and IKBKG as transcriptional regulators of Ripk3 in endothelial cells
por: Gao, Siqi, et al.
Publicado: (2021)

Memory Extinction Entails the Inhibition of the Transcription Factor NF-κB
por: Merlo, Emiliano, et al.
Publicado: (2008)

Transcriptional profiling of the LPS induced NF-κB response in macrophages
por: Sharif, Omar, et al.
Publicado: (2007)

Regulation of Immune Responses by NF-κB/Rel Transcription Factors
por: Sha, William C.
Publicado: (1998)

Octamer-dependent transcription in T cells is mediated by NFAT and NF-κB
por: Mueller, Kerstin, et al.
Publicado: (2013)

Genome-wide predictors of NF-κB recruitment and transcriptional activity
por: Cieślik, Marcin, et al.
Publicado: (2015)

Rel/NF-κB Transcription Factors Emerged at the Onset of Opisthokonts
por: Leger, Michelle M, et al.
Publicado: (2022)

Enhanced transcriptional heterogeneity mediated by NF-κB super-enhancers
por: Wibisana, Johannes N., et al.
Publicado: (2022)

DNA damage independent inhibition of NF-κB transcription by anthracyclines
por: Chora, Angelo Ferreira, et al.
Publicado: (2022)

The levels of NF-κB p50 and NF-κB p65 play a role in thyroid carcinoma malignancy in vivo
por: Le, Fei, et al.
Publicado: (2018)

Chrysin Inhibits NF-κB-Dependent CCL5 Transcription by Targeting IκB Kinase in the Atopic Dermatitis-Like Inflammatory Microenvironment
por: Yeo, Hyunjin, et al.
Publicado: (2020)

Targeting NF-κB pathway for the therapy of diseases: mechanism and clinical study
por: Yu, Hui, et al.
Publicado: (2020)

The NFκB pathway: a therapeutic target in glioblastoma
por: Nogueira, Lorena, et al.
Publicado: (2011)

Targeting NF-κB in glioblastoma: A therapeutic approach
por: Friedmann-Morvinski, Dinorah, et al.
Publicado: (2016)

Targeting constitutive NF-κB specifically in tumor cells
por: Jeong, Ji-Hak, et al.
Publicado: (2017)

Targeting NFκB signaling in GD2(+) BCSCs
por: Nguyen, Khoa, et al.
Publicado: (2017)

Precision Targeting of NF-κB Signaling in Lupus Nephritis
por: Caster, Dawn J., et al.
Publicado: (2020)

LRP16 Integrates into NF-κB Transcriptional Complex and Is Required for Its Functional Activation
por: Wu, Zhiqiang, et al.
Publicado: (2011)

NF-κB and Disease
por: Poma, Paola
Publicado: (2020)

The NF-κB Transcriptional Network Is a High-Dose Vitamin C-Targetable Vulnerability in Breast Cancer
por: Mussa, Ali, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_rdorantri7umfe1qthekdefnce