Bone marrow stromal cells from multiple myeloma patients uniquely induce bortezomib resistant NF-κB activity in myeloma cells

BACKGROUND: Components of the microenvironment such as bone marrow stromal cells (BMSCs) are well known to support multiple myeloma (MM) disease progression and resistance to chemotherapy including the proteasome inhibitor bortezomib. However, functional distinctions between BMSCs in MM patients and...

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Detalles Bibliográficos
Autores principales: Markovina, Stephanie, Callander, Natalie S, O'Connor, Shelby L, Xu, Guangwu, Shi, Yufang, Leith, Catherine P, Kim, KyungMann, Trivedi, Parul, Kim, Jaehyup, Hematti, Peiman, Miyamoto, Shigeki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095250/
https://www.ncbi.nlm.nih.gov/pubmed/20604947
http://dx.doi.org/10.1186/1476-4598-9-176

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