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Differential Requirement for Utrophin in the Induced Pluripotent Stem Cell Correction of Muscle versus Fat in Muscular Dystrophy Mice

Duchenne muscular dystrophy (DMD) is an incurable degenerative muscle disorder. We injected WT mouse induced pluripotent stem cells (iPSCs) into mdx and mdx∶utrophin mutant blastocysts, which are predisposed to develop DMD with an increasing degree of severity (mdx <<< mdx∶utrophin). In mdx...

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Detalles Bibliográficos
Autores principales:	Beck, Amanda J., Vitale, Joseph M., Zhao, Qingshi, Schneider, Joel S., Chang, Corey, Altaf, Aneela, Michaels, Jennifer, Bhaumik, Mantu, Grange, Robert, Fraidenraich, Diego
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095639/ https://www.ncbi.nlm.nih.gov/pubmed/21603573 http://dx.doi.org/10.1371/journal.pone.0020065

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