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Potent Host-Directed Small-Molecule Inhibitors of Myxovirus RNA-Dependent RNA-Polymerases
Therapeutic targeting of host cell factors required for virus replication rather than of pathogen components opens new perspectives to counteract virus infections. Anticipated advantages of this approach include a heightened barrier against the development of viral resistance and a broadened pathoge...
Autores principales: | Krumm, Stefanie A., Ndungu, J. Maina, Yoon, Jeong-Joong, Dochow, Melanie, Sun, Aiming, Natchus, Michael, Snyder, James P., Plemper, Richard K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095640/ https://www.ncbi.nlm.nih.gov/pubmed/21603574 http://dx.doi.org/10.1371/journal.pone.0020069 |
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