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Structure and Activity of a Novel Archaeal β-CASP Protein with N-Terminal KH Domains

MTH1203, a β-CASP metallo-β-lactamase family nuclease from the archaeon Methanothermobacter thermautotrophicus, was identified as a putative nuclease that might contribute to RNA processing. The crystal structure of MTH1203 reveals that, in addition to the metallo-β-lactamase nuclease and the β-CASP...

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Detalles Bibliográficos
Autores principales: Silva, Ana P.G., Chechik, Maria, Byrne, Robert T., Waterman, David G., Ng, C. Leong, Dodson, Eleanor J., Koonin, Eugene V., Antson, Alfred A., Smits, Callum
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095777/
https://www.ncbi.nlm.nih.gov/pubmed/21565697
http://dx.doi.org/10.1016/j.str.2011.03.002