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hTID-1 defines a novel regulator of c-Met Receptor signaling in renal cell carcinomas
The c-Met receptor tyrosine kinase (MetR) is frequently overexpressed and constitutively phosphorylated in a number of human malignancies. Activation of the receptor by its ligand, hepatocyte growth factor (HGF), leads to increased cell proliferation, motility, survival and disruption of adherens ju...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095899/ https://www.ncbi.nlm.nih.gov/pubmed/21242965 http://dx.doi.org/10.1038/onc.2010.601 |