Cancer Stem Cell Radioresistance and Enrichment: Where Frontline Radiation Therapy May Fail in Lung and Esophageal Cancers

Many studies have highlighted the role cancer stem cells (CSC) play in the development and progression of various types of cancer including lung and esophageal cancer. More recently, it has been proposed that the presence of CSCs affects treatment efficacy and patient prognosis. In reviewing this ne...

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Detalles Bibliográficos
Autores principales: Nguyen, Giang Huong, Murph, Mandi M., Chang, Joe Y.
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095975/
https://www.ncbi.nlm.nih.gov/pubmed/21603589
http://dx.doi.org/10.3390/cancers3011232
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author Nguyen, Giang Huong
Murph, Mandi M.
Chang, Joe Y.
author_facet Nguyen, Giang Huong
Murph, Mandi M.
Chang, Joe Y.
author_sort Nguyen, Giang Huong
collection PubMed
description Many studies have highlighted the role cancer stem cells (CSC) play in the development and progression of various types of cancer including lung and esophageal cancer. More recently, it has been proposed that the presence of CSCs affects treatment efficacy and patient prognosis. In reviewing this new area of cancer biology, we will give an overview of the current literature regarding lung and esophageal CSCs and radioresistance of CSC, and discuss the potential therapeutic applications of these findings.
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spelling pubmed-30959752011-05-17 Cancer Stem Cell Radioresistance and Enrichment: Where Frontline Radiation Therapy May Fail in Lung and Esophageal Cancers Nguyen, Giang Huong Murph, Mandi M. Chang, Joe Y. Cancers (Basel) Review Many studies have highlighted the role cancer stem cells (CSC) play in the development and progression of various types of cancer including lung and esophageal cancer. More recently, it has been proposed that the presence of CSCs affects treatment efficacy and patient prognosis. In reviewing this new area of cancer biology, we will give an overview of the current literature regarding lung and esophageal CSCs and radioresistance of CSC, and discuss the potential therapeutic applications of these findings. Molecular Diversity Preservation International (MDPI) 2011-03-10 /pmc/articles/PMC3095975/ /pubmed/21603589 http://dx.doi.org/10.3390/cancers3011232 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Nguyen, Giang Huong
Murph, Mandi M.
Chang, Joe Y.
Cancer Stem Cell Radioresistance and Enrichment: Where Frontline Radiation Therapy May Fail in Lung and Esophageal Cancers
title Cancer Stem Cell Radioresistance and Enrichment: Where Frontline Radiation Therapy May Fail in Lung and Esophageal Cancers
title_full Cancer Stem Cell Radioresistance and Enrichment: Where Frontline Radiation Therapy May Fail in Lung and Esophageal Cancers
title_fullStr Cancer Stem Cell Radioresistance and Enrichment: Where Frontline Radiation Therapy May Fail in Lung and Esophageal Cancers
title_full_unstemmed Cancer Stem Cell Radioresistance and Enrichment: Where Frontline Radiation Therapy May Fail in Lung and Esophageal Cancers
title_short Cancer Stem Cell Radioresistance and Enrichment: Where Frontline Radiation Therapy May Fail in Lung and Esophageal Cancers
title_sort cancer stem cell radioresistance and enrichment: where frontline radiation therapy may fail in lung and esophageal cancers
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095975/
https://www.ncbi.nlm.nih.gov/pubmed/21603589
http://dx.doi.org/10.3390/cancers3011232
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AT murphmandim cancerstemcellradioresistanceandenrichmentwherefrontlineradiationtherapymayfailinlungandesophagealcancers
AT changjoey cancerstemcellradioresistanceandenrichmentwherefrontlineradiationtherapymayfailinlungandesophagealcancers

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