Cargando…
Mechanisms of Neuroprotection by Protein Disulphide Isomerase in Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterised by the progressive loss of motor neurons, leading to paralysis and death within several years of onset. Although protein misfolding is a key feature of ALS, the upstream triggers of disease remain elusive. R...
Autores principales: | Walker, Adam K., Atkin, Julie D. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096316/ https://www.ncbi.nlm.nih.gov/pubmed/21603027 http://dx.doi.org/10.1155/2011/317340 |
Ejemplares similares
-
Protein disulphide isomerase (PDI) is protective against amyotrophic lateral sclerosis (ALS)-related mutant Fused in Sarcoma (FUS) in in vitro models
por: Parakh, S., et al.
Publicado: (2021) -
ER stress and unfolded protein response in amyotrophic lateral sclerosis—a controversial role of protein disulphide isomerase
por: Jaronen, Merja, et al.
Publicado: (2014) -
The Role of S-Nitrosylation and S-Glutathionylation of Protein Disulphide Isomerase in Protein Misfolding and Neurodegeneration
por: Halloran, M., et al.
Publicado: (2013) -
Novel roles for protein disulphide isomerase in disease states: a double edged sword?
por: Parakh, Sonam, et al.
Publicado: (2015) -
Molecular Motor Proteins and Amyotrophic Lateral Sclerosis
por: Soo, Kai Y, et al.
Publicado: (2011)