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hERGAPDbase: a database documenting hERG channel inhibitory potentials and APD-prolongation activities of chemical compounds
Drug-induced QT interval prolongation is one of the most common reasons for the withdrawal of drugs from the market. In the past decade, at least nine drugs, i.e. terfenadine, astemizole, grepafloxacin, terodiline, droperidol, lidoflazine, sertindole, levomethadyl and cisapride, have been removed fr...
Autores principales: | Hishigaki, Haretsugu, Kuhara, Satoru |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096323/ https://www.ncbi.nlm.nih.gov/pubmed/21586548 http://dx.doi.org/10.1093/database/bar017 |
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