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HBx Sensitizes Cells to Oxidative Stress-induced Apoptosis by Accelerating the Loss of Mcl-1 Protein via Caspase-3 Cascade

BACKGROUND: Oxidative stress has been implicated in the pathogenesis of a wide spectrum of human diseases, including Hepatitis B virus (HBV)-related liver disease. Hepatitis B virus X protein (HBx) is a key regulator of HBV that exerts pleiotropic activity on cellular functions. Recent studies showe...

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Detalles Bibliográficos
Autores principales:	Hu, Liang, Chen, Lei, Yang, GuangZhen, Li, Liang, Sun, HanYong, Chang, YanXin, Tu, QianQian, Wu, MengChao, Wang, HongYang
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096594/ https://www.ncbi.nlm.nih.gov/pubmed/21504623 http://dx.doi.org/10.1186/1476-4598-10-43

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