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The P2 Receptor Antagonist PPADS Supports Recovery from Experimental Stroke In Vivo

BACKGROUND: After ischemia of the CNS, extracellular adenosine 5′-triphosphate (ATP) can reach high concentrations due to cell damage and subsequent increase of membrane permeability. ATP may cause cellular degeneration and death, mediated by P2X and P2Y receptors. METHODOLOGY/PRINCIPAL FINDINGS: Th...

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Detalles Bibliográficos
Autores principales:	Lämmer, Alexandra B., Beck, Alexander, Grummich, Benjamin, Förschler, Annette, Krügel, Thomas, Kahn, Thomas, Schneider, Dietmar, Illes, Peter, Franke, Heike, Krügel, Ute
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096654/ https://www.ncbi.nlm.nih.gov/pubmed/21611146 http://dx.doi.org/10.1371/journal.pone.0019983

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