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Effect of the amyloidogenic L75P apolipoprotein A-I variant on HDL subpopulations

BACKGROUND: Hereditary amyloidosis due to mutations of apolipoprotein A-I (apoA-I) is a rare disease characterized by the deposition of amyloid fibrils constituted by the N-terminal fragment of apoA-I in several organs. L75P is a variant of apoA-I associated with systemic amyloidosis predominantly i...

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Detalles Bibliográficos
Autores principales: Gomaraschi, Monica, Obici, Laura, Simonelli, Sara, Gregorini, Gina, Negrinelli, Alessandro, Merlini, Giampaolo, Franceschini, Guido, Calabresi, Laura
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096778/
https://www.ncbi.nlm.nih.gov/pubmed/21458433
http://dx.doi.org/10.1016/j.cca.2011.03.027