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Chromatin remodelling complex dosage modulates transcription factor function in heart development
Dominant mutations in cardiac transcription factor genes cause human inherited congenital heart defects (CHDs); however, their molecular basis is not understood. Interactions between transcription factors and the Brg1/Brm-associated factor (BAF) chromatin remodelling complex suggest potential mechan...
Autores principales: | Takeuchi, Jun K., Lou, Xin, Alexander, Jeffrey M., Sugizaki, Hiroe, Delgado-Olguín, Paul, Holloway, Alisha K., Mori, Alessandro D., Wylie, John N., Munson, Chantilly, Zhu, Yonghong, Zhou, Yu-Qing, Yeh, Ru-Fang, Henkelman, R. Mark, Harvey, Richard P., Metzger, Daniel, Chambon, Pierre, Stainier, Didier Y. R., Pollard, Katherine S., Scott, Ian C., Bruneau, Benoit G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096875/ https://www.ncbi.nlm.nih.gov/pubmed/21304516 http://dx.doi.org/10.1038/ncomms1187 |
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