The alkylphospholipid, perifosine, radiosensitizes prostate cancer cells both in vitro and in vivo

BACKGROUND: Perifosine is a membrane-targeted alkylphospholipid developed to inhibit the PI3K/Akt pathway and has been suggested as a favorable candidate for combined use with radiotherapy. In this study, we investigated the effect of the combined treatment of perifosine and radiation (CTPR) on pros...

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Detalles Bibliográficos
Autores principales: Gao, Yuanhong, Ishiyama, Hiromichi, Sun, Mianen, Brinkman, Kathryn L, Wang, Xiaozhen, Zhu, Julie, Mai, Weiyuan, Huang, Ying, Floryk, Daniel, Ittmann, Michael, Thompson, Timothy C, Butler, E Brian, Xu, Bo, Teh, Bin S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096921/
https://www.ncbi.nlm.nih.gov/pubmed/21496273
http://dx.doi.org/10.1186/1748-717X-6-39

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096921/
https://www.ncbi.nlm.nih.gov/pubmed/21496273
http://dx.doi.org/10.1186/1748-717X-6-39

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