Estimation of affinities of ligands in mixtures via magnetic recovery of target-ligand complexes and chromatographic analyses: chemometrics and an experimental model

ABSTRACT: BACKGROUND: The combinatorial library strategy of using multiple candidate ligands in mixtures as library members is ideal in terms of cost and efficiency, but needs special screening methods to estimate the affinities of candidate ligands in such mixtures. Herein, a new method to screen c...

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Detalles Bibliográficos
Autores principales: Yang, Xiaolan, Xie, Yanling, Pu, Jun, Zhao, Hua, Liao, Juan, Yuan, Yonghua, Zhu, Sha, Long, Gaobo, Zhang, Chun, Yuan, Huidong, Chen, Yiwen, Liao, Fei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096923/
https://www.ncbi.nlm.nih.gov/pubmed/21545719
http://dx.doi.org/10.1186/1472-6750-11-44

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