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Two Naturally Occurring Terpenes, Dehydrocostuslactone and Costunolide, Decrease Intracellular GSH Content and Inhibit STAT3 Activation
The main purpose of the present study is to envisage the molecular mechanism of inhibitory action ofdehydrocostuslactone (DCE) andcostunolide (CS), two naturally occurring sesquiterpene lactones, towards the activation of signal transducer and activator of transcription 3 (STAT3). We report that, in...
Autores principales: | Butturini, Elena, Cavalieri, Elisabetta, Carcereri de Prati, Alessandra, Darra, Elena, Rigo, Antonella, Shoji, Kazuo, Murayama, Norie, Yamazaki, Hiroshi, Watanabe, Yasuo, Suzuki, Hisanori, Mariotto, Sofia |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097233/ https://www.ncbi.nlm.nih.gov/pubmed/21625597 http://dx.doi.org/10.1371/journal.pone.0020174 |
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