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C-Terminus Glycans with Critical Functional Role in the Maturation of Secretory Glycoproteins

The N-glycans of membrane glycoproteins are mainly exposed to the extracellular space. Human tyrosinase is a transmembrane glycoprotein with six or seven bulky N-glycans exposed towards the lumen of subcellular organelles. The central active site region of human tyrosinase is modeled here within les...

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Detalles Bibliográficos
Autores principales: Cioaca, Daniela, Ghenea, Simona, Spiridon, Laurentiu N., Marin, Marioara, Petrescu, Andrei-Jose, Petrescu, Stefana M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097235/
https://www.ncbi.nlm.nih.gov/pubmed/21625599
http://dx.doi.org/10.1371/journal.pone.0019979