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Exploiting Nucleotide Composition to Engineer Promoters
The choice of promoter is a critical step in optimizing the efficiency and stability of recombinant protein production in mammalian cell lines. Artificial promoters that provide stable expression across cell lines and can be designed to the desired strength constitute an alternative to the use of vi...
Autores principales: | Grabherr, Manfred G., Pontiller, Jens, Mauceli, Evan, Ernst, Wolfgang, Baumann, Martina, Biagi, Tara, Swofford, Ross, Russell, Pamela, Zody, Michael C., Di Palma, Federica, Lindblad-Toh, Kerstin, Grabherr, Reingard M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097237/ https://www.ncbi.nlm.nih.gov/pubmed/21625601 http://dx.doi.org/10.1371/journal.pone.0020136 |
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