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Temperature-dependent STIM1 activation induces Ca(2+) influx and modulates gene expression
Intracellular Ca(2+) is essential for diverse cellular functions. Ca(2+) entry into many cell types including immune cells is triggered by depleting endoplasmic reticulum (ER) Ca(2+), a process termed store-operated Ca(2+) entry (SOCE). STIM1 is an ER Ca(2+) sensor. Upon Ca(2+) store depletion, STIM...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097298/ https://www.ncbi.nlm.nih.gov/pubmed/21499266 http://dx.doi.org/10.1038/nchembio.558 |