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Technical approaches for mouse models of human disease
The mouse is the leading organism for disease research. A rich resource of genetic variation occurs naturally in inbred and special strains owing to spontaneous mutations. However, one can also obtain desired gene mutations by using the following processes: targeted mutations that eliminate function...
Autores principales: | Justice, Monica J., Siracusa, Linda D., Stewart, A. Francis |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097452/ https://www.ncbi.nlm.nih.gov/pubmed/21558063 http://dx.doi.org/10.1242/dmm.000901 |
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