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Mammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in mice

Breast cancer is the most common malignancy in women of the Western world. Even though a large percentage of breast cancer patients show pathological complete remission after standard treatment regimes, approximately 30–40% are non-responsive and ultimately develop metastatic disease. To generate a...

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Detalles Bibliográficos
Autores principales:	Derksen, Patrick W. B., Braumuller, Tanya M., van der Burg, Eline, Hornsveld, Marten, Mesman, Elly, Wesseling, Jelle, Krimpenfort, Paul, Jonkers, Jos
Formato:	Texto
Lenguaje:	English
Publicado:	The Company of Biologists Limited 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097456/ https://www.ncbi.nlm.nih.gov/pubmed/21282721 http://dx.doi.org/10.1242/dmm.006395

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