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The Gramine Route to Pyrido[4,3-b]indol-3-ones – Identification of a New Cytotoxic Lead

A novel approach to 3-oxo-γ-carbolines was worked out starting from methyl indol-2-ylacetate via a gramine derivative. After quaternization, ammonia and 4-methoxybenzylamine could be inserted giving appropriate 3-oxo-γ-carbolines. Condensation with 2-chlorobenzaldehyde under microwave irradiation ga...

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Detalles Bibliográficos
Autores principales:	Wollein, Uwe, Bracher, Franz
Formato:	Texto
Lenguaje:	English
Publicado:	Österreichische Apotheker-Verlagsgesellschaft 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097496/ https://www.ncbi.nlm.nih.gov/pubmed/21617772 http://dx.doi.org/10.3797/scipharm.1011-11

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