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A case of organophosphate poisoning presenting with seizure and unavailable history of parenteral suicide attempt

Organophosphate (OP) poisoning is common in India. Only few case reports of parenteral OP poisoning have been described. We report a case of self-injected methyl parathion poisoning, presenting after four days with seizure, altered sensorium, and respiratory distress which posed a diagnostic and the...

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Detalles Bibliográficos
Autores principales: Pandit, Vinay, Seshadri, Shubha, Rao, S N, Samarasinghe, Charmaine, Kumar, Ashwini, Valsalan, Rohith
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097564/
https://www.ncbi.nlm.nih.gov/pubmed/21633583
http://dx.doi.org/10.4103/0974-2700.76825
Descripción
Sumario:Organophosphate (OP) poisoning is common in India. Only few case reports of parenteral OP poisoning have been described. We report a case of self-injected methyl parathion poisoning, presenting after four days with seizure, altered sensorium, and respiratory distress which posed a diagnostic and therapeutic dilemma. Despite nonavailability of history of OP poisoning, he was treated based on suspicion and showed a good clinical response to treatment trial with atropine and pralidoxime, and had a successful recovery. Atypical presentations may be encountered following parenteral administration of OP poison, and even a slight suspicion of this warrants proper investigations and treatment for a favorable outcome. Persistently low plasma cholinesterase level is a useful marker for making the diagnosis.