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The dietary isothiocyanate sulforaphane modulates gene expression and alternative gene splicing in a PTEN null preclinical murine model of prostate cancer

BACKGROUND: Dietary or therapeutic interventions to counteract the loss of PTEN expression could contribute to the prevention of prostate carcinogenesis or reduce the rate of cancer progression. In this study, we investigate the interaction between sulforaphane, a dietary isothiocyanate derived from...

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Detalles Bibliográficos
Autores principales:	Traka, Maria H, Spinks, Caroline A, Doleman, Joanne F, Melchini, Antonietta, Ball, Richard Y, Mills, Robert D, Mithen, Richard F
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098008/ https://www.ncbi.nlm.nih.gov/pubmed/20626841 http://dx.doi.org/10.1186/1476-4598-9-189

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