Cargando…
Anti-apoptotic role of HIF-1 and AP-1 in paclitaxel exposed breast cancer cells under hypoxia
BACKGROUND: Hypoxia is a hallmark of solid tumors and is associated with metastases, therapeutic resistance and poor patient survival. RESULTS: In this study, we showed that hypoxia protected MDA-MB-231 breast cancer cells against paclitaxel- but not epirubicin-induced apoptosis. The possible implic...
| Autores principales: | , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098009/ https://www.ncbi.nlm.nih.gov/pubmed/20626868 http://dx.doi.org/10.1186/1476-4598-9-191 |