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Regulation of Erk1/2 activation by osteopontin in PC3 human prostate cancer cells

BACKGROUND: Osteopontin (OPN) has been shown to play many roles in the progression of cancer. We have recently demonstrated the activation of Akt by OPN. Integrin-linked kinase and PI3-kinase are integral proteins in OPN/AKT pathway in PC3 cells. To investigate the role of the extracellular receptor...

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Detalles Bibliográficos
Autores principales:	Robertson, Brian W, Bonsal, Lauren, Chellaiah, Meenakshi A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098013/ https://www.ncbi.nlm.nih.gov/pubmed/20868520 http://dx.doi.org/10.1186/1476-4598-9-260

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