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Genome scale prediction of substrate specificity for acyl adenylate superfamily of enzymes based on active site residue profiles

BACKGROUND: Enzymes belonging to acyl:CoA synthetase (ACS) superfamily activate wide variety of substrates and play major role in increasing the structural and functional diversity of various secondary metabolites in microbes and plants. However, due to the large sequence divergence within the super...

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Detalles Bibliográficos
Autores principales: Khurana, Pankaj, Gokhale, Rajesh S, Mohanty, Debasisa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098103/
https://www.ncbi.nlm.nih.gov/pubmed/20105319
http://dx.doi.org/10.1186/1471-2105-11-57