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Prion Formation and Polyglutamine Aggregation Are Controlled by Two Classes of Genes
Prions are self-perpetuating aggregated proteins that are not limited to mammalian systems but also exist in lower eukaryotes including yeast. While much work has focused around chaperones involved in prion maintenance, including Hsp104, little is known about factors involved in the appearance of pr...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098188/ https://www.ncbi.nlm.nih.gov/pubmed/21625618 http://dx.doi.org/10.1371/journal.pgen.1001386 |