A −436C>A Polymorphism in the Human FAS Gene Promoter Associated with Severe Childhood Malaria

Human genetics and immune responses are considered to critically influence the outcome of malaria infections including life-threatening syndromes caused by Plasmodium falciparum. An important role in immune regulation is assigned to the apoptosis-signaling cell surface receptor CD95 (Fas, APO-1), en...

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Detalles Bibliográficos
Autores principales: Schuldt, Kathrin, Kretz, Cosima C., Timmann, Christian, Sievertsen, Jürgen, Ehmen, Christa, Esser, Claudia, Loag, Wibke, Ansong, Daniel, Dering, Carmen, Evans, Jennifer, Ziegler, Andreas, May, Jürgen, Krammer, Peter H., Agbenyega, Tsiri, Horstmann, Rolf D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098189/
https://www.ncbi.nlm.nih.gov/pubmed/21625619
http://dx.doi.org/10.1371/journal.pgen.1002066

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